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GLP-1 Drugs: Benefits and Dangers of Weight Medications

GLP-1 drugs for obesityGLP-1 drugs have produced remarkable weight-loss results for many people, but can these medications have serious side effects? Weight-loss medications containing semaglutide, including Wegovy and Ozempic, reduce appetite through several interconnected systems involving the brain, digestive tract, pancreas, hormones, and nerves. 1

Semaglutide does not appear to cross the blood-brain barrier freely. Instead, it can reach or influence selected appetite-regulating areas, including regions of the hypothalamus and brainstem. 2 By affecting appetite and food-reward signaling, the medication can help you feel satisfied with less food and may reduce cravings and eating motivated primarily by pleasure rather than hunger. 3
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  1. Zheng Z, Zong Y, Ma Y, et al. Glucagon-like peptide-1 receptor: mechanisms and advances in therapy. Signal Transduction and Targeted Therapy. 2024;9:234.
  2. He Z, Gao Y, Lieu L, et al. Direct and indirect effects of liraglutide on hypothalamic POMC and NPY/AgRP neurons: implications for energy balance and glucose control. Molecular Metabolism. 2019;28:120-134.
  3. van Bloemendaal L, Veltman DJ, ten Kulve JS, et al. GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans. Diabetes. 2014;63(12):4186-4196.

Gut Microbiota, Vision, and Mental Health

gut microbes and dietDid you know that how well your gut works is directly related to your healthy vision and your healthy brain?

Healthy gut microbiota function is linked to normal central nervous system (CNS) function. The microbiota is defined as all microorganisms in a particular location, such as the GI tract, and their respective genetic material. The microbiome is initially developed transmission through the placenta, amniotic fluid, and meconium. The human gut microbiota comprises more than 100 trillion microorganisms associated with multiple functions, from nutrient metabolism to protection against pathogens.
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Natural Eye Care

NaturalEyeCare™ started in 1999 to help the public and professionals learn about complementary care in eye disease treatment.

The information and recommendations we offer are based on over 30 years of peer review research and personal clinical experience which guides us in providing a valuable resource to our readers, customers and patients regarding maintaining healthy vision naturally.

We believe that vision health is intimately connected to overall mental, physical and spiritual health. Therefore we encourage people to look at their overall lifestyle and diet as part of keeping healthy vision and reducing the risk of eye disease onset. This includes diet, regular exercise, and management of daily stress. If one has health issues such as high blood pressure, a thyroid imbalance, any autoimmune disease and/or are on medication(s), these possible contributions to eye disease should considered when working with your health care professional.

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