Vitamin B12 (1965, 1992) - glaucoma

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Research indicates that a statistically significant number of glaucoma patients with long-term supplementation of Vitamin B12 - 1,500 mcg of vitamin B12 over five years - found improvement in or no further deterioration to eyesight due to glaucoma. This was true although eye pressure remained constant.
Published: Sakai, T. Murata, M., and Amemiya, T. Effect of long-term treatment of glaucoma with vitamin B12. Glaucoma. 14 (1992): 167-70.
1965
This early study found that glaucoma patients who were treated with vitamin B12 for over a 5 year period had improved visual acuity (sharpness), and it also found better overall management of the condition
Oftalmol Zh. 1965; 20(6); Klin Oczna 1974 Nov;44(11):1183-7